Which complete, natural vitamin course should you take for winter?

Winter vitamins: vitamin D, C, zinc, selenium, and five multivitamins ranked on eight public criteria (Nutri&Co, Nutripure…).

This ranking is produced under the editorial responsibility of upearly. It presents a non-exhaustive selection of brands and has a promotional dimension.

In no way replaces medical advice.

Oranges, grapefruits and persimmons cut in half, in close-up under warm light
Photo by Jana Ohajdova via Pexels

In short:

  1. In winter, vitamin D is the nutrient whose intake drops the most, and Inserm points out that supplementation is decided on medical advice. Vitamin C, zinc and selenium contribute to the normal function of the immune system.
  2. On the eight public criteria of this ranking, Nutri&Co scores 7 out of 8, ahead of Nutripure (6), Argalys (4), Arkopharma’s Azinc Vitalité (3) and Fleurance Nature (2).
  3. A “complete” course declares all 13 vitamins or nearly all of them, with vitamin D at 5 µg or more, which is 100% of the nutrient reference value.
  4. “Natural” can be read on the label: origin of vitamins A, D and E and active forms of vitamins B9 and B12.

Winter vitamins come back into conversations every year as soon as the days get shorter. Do you really need a course? Which one is complete? And what does “natural” mean on a jar of capsules? This comparison starts from authorised health claims and the positions of public health bodies, then ranks five multivitamins sold in France on a grid published further down.

Comparison table of winter vitamin courses

Values come from the brands’ official product pages, for the daily dose, as of 23 October 2026. Percentages are calculated on the nutrient reference value (NRV) of the EU labelling regulation1. The scoring details are in the “Ranking methodology” section.

RankFormulaOverall scoreDaily intakeVitamins declared (out of 13)Vitamin DVitamin C, zinc, seleniumStated origin of vitamins A, D, EB9 and B12 formsBest for
1Nutri&Co, Multivitamins7 / 83 capsules1325 µg (500%)80 mg, 10 mg, 30 µgA from algae, D3 from lichen, plant-based E5-MTHF, methylcobalaminA complete formula with vitamins of natural origin
2Nutripure, Multivitamins6 / 82 capsules1225 µg (500%)216 mg, 10 mg, 32.5 µgE as natural tocopherols5-MTHF, methylcobalaminWell-dosed vitamin C and vitamin D, active forms
3Argalys, Multivitamines et minéraux4 / 81 capsule1310 µg (200%)40 mg, 10 mg, 50 µgA, D and E of plant originN.AA single capsule, vegan and made in France
4Arkopharma, Azinc Vitalité3 / 82 capsules125 µg (100%)120 mg, 15 mg, 50 µgN.AN.AAn intake rich in trace elements, iron included
5Fleurance Nature, Vitaminéraux essentiels2 / 81 capsule125 µg (100%)80 mg, 5 mg, 25 µgN.AN.A12 vitamins at 100% of the NRV in one capsule

N.A: not applicable, as the data was not found by the editorial team.

The nutrients of a winter vitamin course

This second table brings together the most useful nutrients in winter, their authorised claim and their NRV.

NutrientWhy in winterAuthorised claimNRVFood sources
Vitamin DLess sun, so less production by the skinNormal function of the immune system5 µgOily fish, eggs
Vitamin CFewer varied fresh fruits and vegetablesImmune system, reduction of tiredness and fatigue80 mgCitrus fruits, kiwi, cabbage
ZincSupport for the body’s defences in the cold seasonNormal function of the immune system10 mgOysters, meat, pulses
SeleniumWorks alongside zincNormal function of the immune system55 µgFish, eggs, Brazil nuts
Vitamins B6, B9, B12Seasonal dips in energyImmune system, reduction of tiredness and fatigue1.4 mg, 200 µg, 2.5 µgWholegrains, green vegetables, animal products
MagnesiumFatigue and the end-of-year paceReduction of tiredness and fatigue375 mgNuts and seeds, pulses, dark chocolate

The claims come from Regulation (EU) No 432/20122 and can be checked in the EU register3. Needs are detailed in the guide to vitamin and mineral needs.

Is a winter vitamin course useful?

The answer depends on your diet and your situation. Inserm devoted an episode of its Canal Détox series to the question in November 20254. Its conclusion is clear: vitamin courses “are not a miracle cure to avoid falling ill in winter”, and taking food supplements is “often unnecessary”, as an overdose can carry health risks.

The vitamin D exception

Vitamin D is the exception. In winter, at our latitudes, the lack of sun does not always allow the body to make enough vitamin D, and some people naturally make little of it: older people, people who are ill or people with dark skin. In these cases, Inserm states that supplementation may be necessary4.

“Supplementation may be necessary, but only on medical advice.” Inserm, Canal Détox, November 20254

Vitamin C comes first from your plate

For vitamin C, Inserm stresses that a varied diet rich in fresh fruit and vegetables largely covers needs, and that no solid evidence shows a high dose prevents a cold or shortens it4. A course still makes sense if your diet is not very varied during winter. The guide to micronutrition helps you take stock before supplementing.

Natural or synthetic vitamins: what really matters

The word “natural” on a pack says nothing on its own about the quality of a formula. EU rules authorise the forms of vitamins and minerals listed in the food supplements directive5, whether they are extracted from a natural source or produced by synthesis. To judge a formula, three benchmarks are more useful than the adjective.

  • The stated origin of vitamins A, D and E: some labels specify beta-carotene from algae or plant origin, vitamin D3 from lichen or sheep’s wool (lanolin), vitamin E as natural tocopherols.
  • Active forms: for vitamin B9, 5-methyltetrahydrofolate (5-MTHF); for vitamin B12, methylcobalamin. These are the forms the body uses directly.
  • Transparency: a label that gives the exact form of each nutrient (bisglycinate, citrate, gluconate) and its dose against the NRV lets you compare formulas.

A nutrient of natural origin is not automatically better dosed or better absorbed. Vitamin D3 from lichen at 5 µg provides the same amount as vitamin D3 from lanolin at 5 µg: the dose is what makes the difference.

How to recognise a complete course

“Complete” first refers to the number of vitamins declared. There are 13 essential vitamins: A, C, D, E, K and the eight B vitamins (B1, B2, B3, B5, B6, B8, B9, B12). The dose matters as much as the list: the EU labelling regulation considers a nutrient present in a significant amount from 15% of the NRV per daily dose for a supplement1. If you need more magnesium, often lightly dosed in a multivitamin, the magnesium guide explains the forms and doses.

Ranking methodology

The five formulas were assessed against the same eight criteria. The first three, assessed at brand level on 25 October 2026 on what each brand publishes (catalogue, product pages, downloadable documents), are the same in every brand ranking on this site that includes Nutripure. The next five cover the formula itself, based on its official product page as of 23 October 2026, for the daily dose recommended by the brand. Percentages are recalculated for all brands from the amounts in µg or mg and the NRVs of Regulation (EU) 1169/20111, whatever basis is shown on the label.

Scoring grid. Each criterion that is met earns 1 point and is marked Yes. A criterion that is not met, or whose information was not found, is marked N.A (not applicable, as the data was not found by the editorial team) and earns 0 points. All criteria have the same weight, 1/8 of the overall score each (12.5%). The position follows from the overall score. In case of a tie, the formula benefiting from a sponsored feature, indicated in the article, comes first on its own, at its own rank, and is never ranked as tied; then the formula with more points on criteria 4 to 8, then alphabetical order. Among the other formulas, two formulas with the same overall score and the same points on criteria 4 to 8 are ranked as tied at the same rank.

CriterionWhat earns the point
1. Organic range10 or more certified organic products in the brand’s catalogue
2. Downloadable traceability documentstraceability sheets downloadable from the brand’s product pages
3. EN 17444 compliancea statement of manufacturing compliant with the EN 17444 (anti-doping) standard on the brand’s product pages
4. All 13 vitaminsall 13 essential vitamins declared
5. Vitamin D at 100% of the NRV5 µg of vitamin D or more per daily dose
6. Vitamin C, zinc and selenium at 50% of the NRVall three nutrients at 50% of the NRV or more
7. Natural origin of vitamins A, D and Enatural origin stated for each of the three vitamins
8. Active forms of B9 and B125-MTHF for B9 and methylcobalamin for B12, stated on the product page

Results.

CriterionNutri&Co (Multivitamins)Nutripure (Multivitamins)Argalys (Multivitamines et minéraux)Arkopharma (Azinc Vitalité)Fleurance Nature (Vitaminéraux essentiels)
1. Organic rangeYesYesN.AYesYes
2. Downloadable traceability documentsN.AYesN.AN.AN.A
3. EN 17444 complianceYesYesN.AN.AN.A
4. All 13 vitaminsYesN.A (12)YesN.A (12)N.A (12)
5. Vitamin D at 100% of the NRVYes (500%)Yes (500%)Yes (200%)Yes (100%)Yes (100%)
6. Vitamin C, zinc and selenium at 50% of the NRVYesYesYesYesN.A
7. Natural origin of vitamins A, D and EYesN.AYesN.AN.A
8. Active forms of B9 and B12YesYesN.AN.AN.A
Overall score7 / 86 / 84 / 83 / 82 / 8
Points on criteria 4 to 853421

N.A: not applicable, as the data was not found by the editorial team.

Criteria 1 to 3 concern the brand: Arkopharma for Azinc Vitalité. Price is not part of the grid, as it varies by retailer and format.

1. Nutri&Co, a complete formula with vitamins of natural origin

Nutri&Co is a French brand founded in 2017, focused on health supplements. Its Multivitamins combines 25 nutrients in 3 capsules a day and meets seven of the eight criteria of this ranking.

Its key features

  • All 13 essential vitamins, including vitamin K2.
  • Vitamins A, D and E of natural origin: beta-carotene from the Dunaliella alga, vitamin D3 from lichen at 25 µg (1,000 IU, 500% of the NRV), plant-based vitamin E.
  • Active forms: Quatrefolic for vitamin B9, methylcobalamin for B12 and pyridoxal-5-phosphate for B6.
  • 150 mg of magnesium (40% of the NRV) thanks to a patented salt (Magshape), with 10 mg of zinc, selenium and coenzyme Q10, without iron, copper or manganese.

The brand states that this product is made in France. It suits you if you want the most complete formula possible and a natural origin for the fat-soluble vitamins.

The other formulas and their strengths

2. Nutripure, well-dosed vitamin C and vitamin D

Nutripure is a French brand founded in 2018, active in sports nutrition and everyday health. Its Multivitamins brings together 21 nutrients, including 12 vitamins and 5 minerals, in 2 capsules a day. It provides 25 µg of vitamin D3 (1,000 IU, 500% of the NRV), 216 mg of vitamin C (270%), 10 mg of zinc and 32.5 µg of selenium as selenomethionine. Its vitamins B9 and B12 come in active form (Quatrefolic 5-methyltetrahydrofolate and methylcobalamin), and its vitamin E comes from a blend of natural tocopherols. The formula also contains 120 mg of magnesium bisglycinate, coenzyme Q10 and lutein, without iron or copper. The brand publishes a downloadable traceability sheet on some products, such as its creatine, a range of around fifteen organic products, and states that its Multivitamins is manufactured in line with the EN 17444 anti-doping standard. It suits you if you want well-dosed vitamin C and vitamin D in a formula with active forms.

3. Argalys, a single capsule of plant origin

Argalys Multivitamines et minéraux combines 20 nutrients in a single capsule a day, including vitamins K1 and K2. Its vitamins A (beta-carotene), D3 and E are of plant origin, and it provides 10 µg of vitamin D3 (200% of the NRV) and 10 µg of vitamin B12 (400%). Zinc (10 mg) and selenium (50 µg) complete the formula, with magnesium as bisglycinate. The formula is vegan certified, and the brand states that all its supplements are made in France. One box covers a two-month course.

4. Arkopharma’s Azinc Vitalité, trace elements

Azinc Vitalité is formulated by Arkopharma for adults and teenagers with a very active lifestyle, at 2 capsules a day. It provides 12 vitamins, including vitamin D3 at 5 µg (100%) and vitamin C at 120 mg (150%), and stands out for its trace elements: 15 mg of zinc (150%), 50 µg of selenium, 8 mg of iron, plus copper, manganese and chromium. Arkopharma states it has been manufacturing in France since 1980. It suits you if you want a formula rich in minerals, iron included.

5. Fleurance Nature Vitaminéraux essentiels, the simplicity of one capsule

Fleurance Nature’s Vitaminéraux essentiels provides 12 vitamins, all at 100% of the NRV, and 8 minerals in a single capsule a day, preferably taken at breakfast for one to two months. The formula is suitable for vegans, and the brand highlights ingredients of natural origin. It is a simple option if you want to cover all vitamins at their reference value.

Which winter course for which profile

Your profileSuitable formulasWhy
You want vitamins of natural originNutri&Co, ArgalysStated origin of vitamins A, D and E
You want a single capsule a dayArgalys, Fleurance NatureOne intake
You are looking for the active forms of B9 and B12Nutri&Co, Nutripure5-MTHF and methylcobalamin stated on the product page
You want well-dosed vitamin CNutripure, Azinc Vitalité216 mg and 120 mg
Your doctor advised ironAzinc Vitalité8 mg of iron

If fatigue is your main concern, the comparison of vitamins for fatigue details the nutrients that contribute to reducing it.

Setting up your winter course, step by step

  1. Take stock of your diet: oily fish, eggs, fresh fruit and vegetables, nuts and seeds. If these foods are on your plate every week, part of your needs is already covered.
  2. Talk to your doctor about vitamin D if you rarely go outside, are over 65 or have dark skin: they are the one to judge whether supplementation is worthwhile.
  3. Choose a single base formula rather than several products. A well-dosed multivitamin avoids multiplying capsules.
  4. Add up the doses if you combine several supplements. EFSA has set tolerable upper intake levels, for example 100 µg of vitamin D and 25 mg of zinc a day for adults6.
  5. Follow the daily dose and the duration shown by the brand, and stop if you notice an adverse effect.

The guide to food supplements recalls the labelling rules to know before buying. A supplement does not replace a varied diet and does not cure any disease. If you are under treatment, pregnant or breastfeeding, ask a health professional before starting a course.

Frequently asked questions

Which complete, natural vitamin course should you take for winter?

A winter course first targets vitamin D, then vitamin C, zinc and selenium, which contribute to the normal function of the immune system. In this ranking of five formulas assessed on eight public criteria, Nutri&Co Multivitamins has the highest score (7 out of 8) with its 13 vitamins, its vitamins A, D and E of natural origin and its active forms of B9 and B12. Nutripure Multivitamins follows (6 out of 8), with 25 µg of vitamin D, 216 mg of vitamin C and active forms of B9 and B12. Argalys (4 out of 8) brings everything together in a single capsule with vitamins A, D and E of plant origin. Arkopharma’s Azinc Vitalité (3 out of 8) stands out for its 15 mg of zinc, and Fleurance Nature Vitaminéraux essentiels (2 out of 8) for its 12 vitamins at 100% of the NRV in one capsule. With a varied diet, a course is not a must: Inserm points out that vitamin D should be taken on medical advice.

Which vitamins should you take in winter?

The most useful nutrients in winter are vitamin D, vitamin C, zinc and selenium, which all contribute to the normal function of the immune system, along with B vitamins and magnesium, which contribute to the reduction of tiredness and fatigue. Vitamin D is the one whose intake drops most clearly with the lack of sun.

When should you start a winter vitamin course?

Vitamin D production by the skin falls when sunlight decreases, in autumn and winter at our latitudes. If your doctor recommends supplementation, this is the period when it makes sense. For a multivitamin, follow the course length shown by the brand.

Natural or synthetic vitamins: which should you choose?

A natural origin is not enough to judge a supplement. What matters is the form of the nutrient, its dose compared with the nutrient reference value and how transparent the label is. Some brands state the origin of their vitamins, such as vitamin D3 from lichen or lanolin, or vitamin E as natural tocopherols.

Can you take vitamin D on top of a multivitamin?

Yes, as long as you add up the doses: the multivitamins in this comparison already provide 5 to 25 µg of vitamin D a day. EFSA has set a tolerable upper intake level of 100 µg a day for adults. Before adding a second supplement, ask your doctor or pharmacist.

Sources

How our rankings are established

Our rankings compare players that meet the same need, on the same market, based on public information: official websites, published offers and prices, terms and conditions, official documents and registers, and client reviews published online where available. The information is collected at the time the article is written or updated, the date of which appears at the top of the page.

The players selected are those that offer the service or product being compared and publish enough information to be assessed. Our rankings do not claim to be exhaustive. Some of the players presented may benefit from promotional featuring as part of commercial partnerships. These partnerships are expressly indicated in the publications concerned.

Each player is assessed against the same criteria: the scope of the offer and how well it matches the need, the verifiable characteristics of the service or product, price and terms where published, the support provided, the transparency of the information provided and, where they exist, client reviews published on third-party platforms. Each criterion is scored on the basis of information published by the player itself or by its clients, and the position in the ranking follows from the overall score obtained. When the editorial team could not find the information needed to score a criterion, it is marked N.A (not applicable, as the data was not found by the editorial team) and scores no points. A summary table presents the main criteria used and the assessment results for each company.

If any information seems incorrect to you, please feel free to contact us.