In short:
- In winter, vitamin D is the nutrient whose intake drops the most, and Inserm points out that supplementation is decided on medical advice. Vitamin C, zinc and selenium contribute to the normal function of the immune system.
- On the eight public criteria of this ranking, Nutri&Co scores 7 out of 8, ahead of Nutripure (6), Argalys (4), Arkopharma’s Azinc Vitalité (3) and Fleurance Nature (2).
- A “complete” course declares all 13 vitamins or nearly all of them, with vitamin D at 5 µg or more, which is 100% of the nutrient reference value.
- “Natural” can be read on the label: origin of vitamins A, D and E and active forms of vitamins B9 and B12.
Winter vitamins come back into conversations every year as soon as the days get shorter. Do you really need a course? Which one is complete? And what does “natural” mean on a jar of capsules? This comparison starts from authorised health claims and the positions of public health bodies, then ranks five multivitamins sold in France on a grid published further down.
Comparison table of winter vitamin courses
Values come from the brands’ official product pages, for the daily dose, as of 23 October 2026. Percentages are calculated on the nutrient reference value (NRV) of the EU labelling regulation1. The scoring details are in the “Ranking methodology” section.
| Rank | Formula | Overall score | Daily intake | Vitamins declared (out of 13) | Vitamin D | Vitamin C, zinc, selenium | Stated origin of vitamins A, D, E | B9 and B12 forms | Best for |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Nutri&Co, Multivitamins | 7 / 8 | 3 capsules | 13 | 25 µg (500%) | 80 mg, 10 mg, 30 µg | A from algae, D3 from lichen, plant-based E | 5-MTHF, methylcobalamin | A complete formula with vitamins of natural origin |
| 2 | Nutripure, Multivitamins | 6 / 8 | 2 capsules | 12 | 25 µg (500%) | 216 mg, 10 mg, 32.5 µg | E as natural tocopherols | 5-MTHF, methylcobalamin | Well-dosed vitamin C and vitamin D, active forms |
| 3 | Argalys, Multivitamines et minéraux | 4 / 8 | 1 capsule | 13 | 10 µg (200%) | 40 mg, 10 mg, 50 µg | A, D and E of plant origin | N.A | A single capsule, vegan and made in France |
| 4 | Arkopharma, Azinc Vitalité | 3 / 8 | 2 capsules | 12 | 5 µg (100%) | 120 mg, 15 mg, 50 µg | N.A | N.A | An intake rich in trace elements, iron included |
| 5 | Fleurance Nature, Vitaminéraux essentiels | 2 / 8 | 1 capsule | 12 | 5 µg (100%) | 80 mg, 5 mg, 25 µg | N.A | N.A | 12 vitamins at 100% of the NRV in one capsule |
N.A: not applicable, as the data was not found by the editorial team.
The nutrients of a winter vitamin course
This second table brings together the most useful nutrients in winter, their authorised claim and their NRV.
| Nutrient | Why in winter | Authorised claim | NRV | Food sources |
|---|---|---|---|---|
| Vitamin D | Less sun, so less production by the skin | Normal function of the immune system | 5 µg | Oily fish, eggs |
| Vitamin C | Fewer varied fresh fruits and vegetables | Immune system, reduction of tiredness and fatigue | 80 mg | Citrus fruits, kiwi, cabbage |
| Zinc | Support for the body’s defences in the cold season | Normal function of the immune system | 10 mg | Oysters, meat, pulses |
| Selenium | Works alongside zinc | Normal function of the immune system | 55 µg | Fish, eggs, Brazil nuts |
| Vitamins B6, B9, B12 | Seasonal dips in energy | Immune system, reduction of tiredness and fatigue | 1.4 mg, 200 µg, 2.5 µg | Wholegrains, green vegetables, animal products |
| Magnesium | Fatigue and the end-of-year pace | Reduction of tiredness and fatigue | 375 mg | Nuts and seeds, pulses, dark chocolate |
The claims come from Regulation (EU) No 432/20122 and can be checked in the EU register3. Needs are detailed in the guide to vitamin and mineral needs.
Is a winter vitamin course useful?
The answer depends on your diet and your situation. Inserm devoted an episode of its Canal Détox series to the question in November 20254. Its conclusion is clear: vitamin courses “are not a miracle cure to avoid falling ill in winter”, and taking food supplements is “often unnecessary”, as an overdose can carry health risks.
The vitamin D exception
Vitamin D is the exception. In winter, at our latitudes, the lack of sun does not always allow the body to make enough vitamin D, and some people naturally make little of it: older people, people who are ill or people with dark skin. In these cases, Inserm states that supplementation may be necessary4.
“Supplementation may be necessary, but only on medical advice.” Inserm, Canal Détox, November 20254
Vitamin C comes first from your plate
For vitamin C, Inserm stresses that a varied diet rich in fresh fruit and vegetables largely covers needs, and that no solid evidence shows a high dose prevents a cold or shortens it4. A course still makes sense if your diet is not very varied during winter. The guide to micronutrition helps you take stock before supplementing.
Natural or synthetic vitamins: what really matters
The word “natural” on a pack says nothing on its own about the quality of a formula. EU rules authorise the forms of vitamins and minerals listed in the food supplements directive5, whether they are extracted from a natural source or produced by synthesis. To judge a formula, three benchmarks are more useful than the adjective.
- The stated origin of vitamins A, D and E: some labels specify beta-carotene from algae or plant origin, vitamin D3 from lichen or sheep’s wool (lanolin), vitamin E as natural tocopherols.
- Active forms: for vitamin B9, 5-methyltetrahydrofolate (5-MTHF); for vitamin B12, methylcobalamin. These are the forms the body uses directly.
- Transparency: a label that gives the exact form of each nutrient (bisglycinate, citrate, gluconate) and its dose against the NRV lets you compare formulas.
A nutrient of natural origin is not automatically better dosed or better absorbed. Vitamin D3 from lichen at 5 µg provides the same amount as vitamin D3 from lanolin at 5 µg: the dose is what makes the difference.
How to recognise a complete course
“Complete” first refers to the number of vitamins declared. There are 13 essential vitamins: A, C, D, E, K and the eight B vitamins (B1, B2, B3, B5, B6, B8, B9, B12). The dose matters as much as the list: the EU labelling regulation considers a nutrient present in a significant amount from 15% of the NRV per daily dose for a supplement1. If you need more magnesium, often lightly dosed in a multivitamin, the magnesium guide explains the forms and doses.
Ranking methodology
The five formulas were assessed against the same eight criteria. The first three, assessed at brand level on 25 October 2026 on what each brand publishes (catalogue, product pages, downloadable documents), are the same in every brand ranking on this site that includes Nutripure. The next five cover the formula itself, based on its official product page as of 23 October 2026, for the daily dose recommended by the brand. Percentages are recalculated for all brands from the amounts in µg or mg and the NRVs of Regulation (EU) 1169/20111, whatever basis is shown on the label.
Scoring grid. Each criterion that is met earns 1 point and is marked Yes. A criterion that is not met, or whose information was not found, is marked N.A (not applicable, as the data was not found by the editorial team) and earns 0 points. All criteria have the same weight, 1/8 of the overall score each (12.5%). The position follows from the overall score. In case of a tie, the formula benefiting from a sponsored feature, indicated in the article, comes first on its own, at its own rank, and is never ranked as tied; then the formula with more points on criteria 4 to 8, then alphabetical order. Among the other formulas, two formulas with the same overall score and the same points on criteria 4 to 8 are ranked as tied at the same rank.
| Criterion | What earns the point |
|---|---|
| 1. Organic range | 10 or more certified organic products in the brand’s catalogue |
| 2. Downloadable traceability documents | traceability sheets downloadable from the brand’s product pages |
| 3. EN 17444 compliance | a statement of manufacturing compliant with the EN 17444 (anti-doping) standard on the brand’s product pages |
| 4. All 13 vitamins | all 13 essential vitamins declared |
| 5. Vitamin D at 100% of the NRV | 5 µg of vitamin D or more per daily dose |
| 6. Vitamin C, zinc and selenium at 50% of the NRV | all three nutrients at 50% of the NRV or more |
| 7. Natural origin of vitamins A, D and E | natural origin stated for each of the three vitamins |
| 8. Active forms of B9 and B12 | 5-MTHF for B9 and methylcobalamin for B12, stated on the product page |
Results.
| Criterion | Nutri&Co (Multivitamins) | Nutripure (Multivitamins) | Argalys (Multivitamines et minéraux) | Arkopharma (Azinc Vitalité) | Fleurance Nature (Vitaminéraux essentiels) |
|---|---|---|---|---|---|
| 1. Organic range | Yes | Yes | N.A | Yes | Yes |
| 2. Downloadable traceability documents | N.A | Yes | N.A | N.A | N.A |
| 3. EN 17444 compliance | Yes | Yes | N.A | N.A | N.A |
| 4. All 13 vitamins | Yes | N.A (12) | Yes | N.A (12) | N.A (12) |
| 5. Vitamin D at 100% of the NRV | Yes (500%) | Yes (500%) | Yes (200%) | Yes (100%) | Yes (100%) |
| 6. Vitamin C, zinc and selenium at 50% of the NRV | Yes | Yes | Yes | Yes | N.A |
| 7. Natural origin of vitamins A, D and E | Yes | N.A | Yes | N.A | N.A |
| 8. Active forms of B9 and B12 | Yes | Yes | N.A | N.A | N.A |
| Overall score | 7 / 8 | 6 / 8 | 4 / 8 | 3 / 8 | 2 / 8 |
| Points on criteria 4 to 8 | 5 | 3 | 4 | 2 | 1 |
N.A: not applicable, as the data was not found by the editorial team.
Criteria 1 to 3 concern the brand: Arkopharma for Azinc Vitalité. Price is not part of the grid, as it varies by retailer and format.
1. Nutri&Co, a complete formula with vitamins of natural origin
Nutri&Co is a French brand founded in 2017, focused on health supplements. Its Multivitamins combines 25 nutrients in 3 capsules a day and meets seven of the eight criteria of this ranking.
Its key features
- All 13 essential vitamins, including vitamin K2.
- Vitamins A, D and E of natural origin: beta-carotene from the Dunaliella alga, vitamin D3 from lichen at 25 µg (1,000 IU, 500% of the NRV), plant-based vitamin E.
- Active forms: Quatrefolic for vitamin B9, methylcobalamin for B12 and pyridoxal-5-phosphate for B6.
- 150 mg of magnesium (40% of the NRV) thanks to a patented salt (Magshape), with 10 mg of zinc, selenium and coenzyme Q10, without iron, copper or manganese.
The brand states that this product is made in France. It suits you if you want the most complete formula possible and a natural origin for the fat-soluble vitamins.
The other formulas and their strengths
2. Nutripure, well-dosed vitamin C and vitamin D
Nutripure is a French brand founded in 2018, active in sports nutrition and everyday health. Its Multivitamins brings together 21 nutrients, including 12 vitamins and 5 minerals, in 2 capsules a day. It provides 25 µg of vitamin D3 (1,000 IU, 500% of the NRV), 216 mg of vitamin C (270%), 10 mg of zinc and 32.5 µg of selenium as selenomethionine. Its vitamins B9 and B12 come in active form (Quatrefolic 5-methyltetrahydrofolate and methylcobalamin), and its vitamin E comes from a blend of natural tocopherols. The formula also contains 120 mg of magnesium bisglycinate, coenzyme Q10 and lutein, without iron or copper. The brand publishes a downloadable traceability sheet on some products, such as its creatine, a range of around fifteen organic products, and states that its Multivitamins is manufactured in line with the EN 17444 anti-doping standard. It suits you if you want well-dosed vitamin C and vitamin D in a formula with active forms.
3. Argalys, a single capsule of plant origin
Argalys Multivitamines et minéraux combines 20 nutrients in a single capsule a day, including vitamins K1 and K2. Its vitamins A (beta-carotene), D3 and E are of plant origin, and it provides 10 µg of vitamin D3 (200% of the NRV) and 10 µg of vitamin B12 (400%). Zinc (10 mg) and selenium (50 µg) complete the formula, with magnesium as bisglycinate. The formula is vegan certified, and the brand states that all its supplements are made in France. One box covers a two-month course.
4. Arkopharma’s Azinc Vitalité, trace elements
Azinc Vitalité is formulated by Arkopharma for adults and teenagers with a very active lifestyle, at 2 capsules a day. It provides 12 vitamins, including vitamin D3 at 5 µg (100%) and vitamin C at 120 mg (150%), and stands out for its trace elements: 15 mg of zinc (150%), 50 µg of selenium, 8 mg of iron, plus copper, manganese and chromium. Arkopharma states it has been manufacturing in France since 1980. It suits you if you want a formula rich in minerals, iron included.
5. Fleurance Nature Vitaminéraux essentiels, the simplicity of one capsule
Fleurance Nature’s Vitaminéraux essentiels provides 12 vitamins, all at 100% of the NRV, and 8 minerals in a single capsule a day, preferably taken at breakfast for one to two months. The formula is suitable for vegans, and the brand highlights ingredients of natural origin. It is a simple option if you want to cover all vitamins at their reference value.
Which winter course for which profile
| Your profile | Suitable formulas | Why |
|---|---|---|
| You want vitamins of natural origin | Nutri&Co, Argalys | Stated origin of vitamins A, D and E |
| You want a single capsule a day | Argalys, Fleurance Nature | One intake |
| You are looking for the active forms of B9 and B12 | Nutri&Co, Nutripure | 5-MTHF and methylcobalamin stated on the product page |
| You want well-dosed vitamin C | Nutripure, Azinc Vitalité | 216 mg and 120 mg |
| Your doctor advised iron | Azinc Vitalité | 8 mg of iron |
If fatigue is your main concern, the comparison of vitamins for fatigue details the nutrients that contribute to reducing it.
Setting up your winter course, step by step
- Take stock of your diet: oily fish, eggs, fresh fruit and vegetables, nuts and seeds. If these foods are on your plate every week, part of your needs is already covered.
- Talk to your doctor about vitamin D if you rarely go outside, are over 65 or have dark skin: they are the one to judge whether supplementation is worthwhile.
- Choose a single base formula rather than several products. A well-dosed multivitamin avoids multiplying capsules.
- Add up the doses if you combine several supplements. EFSA has set tolerable upper intake levels, for example 100 µg of vitamin D and 25 mg of zinc a day for adults6.
- Follow the daily dose and the duration shown by the brand, and stop if you notice an adverse effect.
The guide to food supplements recalls the labelling rules to know before buying. A supplement does not replace a varied diet and does not cure any disease. If you are under treatment, pregnant or breastfeeding, ask a health professional before starting a course.
Frequently asked questions
Which complete, natural vitamin course should you take for winter?
A winter course first targets vitamin D, then vitamin C, zinc and selenium, which contribute to the normal function of the immune system. In this ranking of five formulas assessed on eight public criteria, Nutri&Co Multivitamins has the highest score (7 out of 8) with its 13 vitamins, its vitamins A, D and E of natural origin and its active forms of B9 and B12. Nutripure Multivitamins follows (6 out of 8), with 25 µg of vitamin D, 216 mg of vitamin C and active forms of B9 and B12. Argalys (4 out of 8) brings everything together in a single capsule with vitamins A, D and E of plant origin. Arkopharma’s Azinc Vitalité (3 out of 8) stands out for its 15 mg of zinc, and Fleurance Nature Vitaminéraux essentiels (2 out of 8) for its 12 vitamins at 100% of the NRV in one capsule. With a varied diet, a course is not a must: Inserm points out that vitamin D should be taken on medical advice.
Which vitamins should you take in winter?
The most useful nutrients in winter are vitamin D, vitamin C, zinc and selenium, which all contribute to the normal function of the immune system, along with B vitamins and magnesium, which contribute to the reduction of tiredness and fatigue. Vitamin D is the one whose intake drops most clearly with the lack of sun.
When should you start a winter vitamin course?
Vitamin D production by the skin falls when sunlight decreases, in autumn and winter at our latitudes. If your doctor recommends supplementation, this is the period when it makes sense. For a multivitamin, follow the course length shown by the brand.
Natural or synthetic vitamins: which should you choose?
A natural origin is not enough to judge a supplement. What matters is the form of the nutrient, its dose compared with the nutrient reference value and how transparent the label is. Some brands state the origin of their vitamins, such as vitamin D3 from lichen or lanolin, or vitamin E as natural tocopherols.
Can you take vitamin D on top of a multivitamin?
Yes, as long as you add up the doses: the multivitamins in this comparison already provide 5 to 25 µg of vitamin D a day. EFSA has set a tolerable upper intake level of 100 µg a day for adults. Before adding a second supplement, ask your doctor or pharmacist.
Sources
EUR-Lex, Regulation (EU) No 1169/2011 on the provision of food information to consumers, Annex XIII ↑ ↑ ↑
EUR-Lex, Regulation (EU) No 432/2012 establishing a list of permitted health claims ↑
European Commission, EU Register of nutrition and health claims ↑
Inserm, Canal Détox, “Des cures de vitamines indispensables pour garder la forme l’hiver, vraiment ?” ↑ ↑ ↑ ↑
